Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report

• Paraneoplastic Cushing's syndrome is rarely seen in gynecologic cancers, appearing only in case reports; • It almost universally results in acute decompensation and portends a poor prognosis; • We describe a patient with metastatic endometrial carcinoma with both paraneoplastic Cushing's...

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Autores principales: Mitchell, Evelyn, Ciccone, Marcia, Zhang, Bing, Tsai, Arnold, Brunette, Laurie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620411/
https://www.ncbi.nlm.nih.gov/pubmed/31334321
http://dx.doi.org/10.1016/j.gore.2019.06.005
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author Mitchell, Evelyn
Ciccone, Marcia
Zhang, Bing
Tsai, Arnold
Brunette, Laurie L.
author_facet Mitchell, Evelyn
Ciccone, Marcia
Zhang, Bing
Tsai, Arnold
Brunette, Laurie L.
author_sort Mitchell, Evelyn
collection PubMed
description • Paraneoplastic Cushing's syndrome is rarely seen in gynecologic cancers, appearing only in case reports; • It almost universally results in acute decompensation and portends a poor prognosis; • We describe a patient with metastatic endometrial carcinoma with both paraneoplastic Cushing's syndrome and hypercalcemia; • High clinical suspicion for malignancy is essential, as these syndromes improve with treatment of the underlying malignancy.
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spelling pubmed-66204112019-07-22 Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report Mitchell, Evelyn Ciccone, Marcia Zhang, Bing Tsai, Arnold Brunette, Laurie L. Gynecol Oncol Rep Case Report • Paraneoplastic Cushing's syndrome is rarely seen in gynecologic cancers, appearing only in case reports; • It almost universally results in acute decompensation and portends a poor prognosis; • We describe a patient with metastatic endometrial carcinoma with both paraneoplastic Cushing's syndrome and hypercalcemia; • High clinical suspicion for malignancy is essential, as these syndromes improve with treatment of the underlying malignancy. Elsevier 2019-06-18 /pmc/articles/PMC6620411/ /pubmed/31334321 http://dx.doi.org/10.1016/j.gore.2019.06.005 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Mitchell, Evelyn
Ciccone, Marcia
Zhang, Bing
Tsai, Arnold
Brunette, Laurie L.
Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report
title Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report
title_full Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report
title_fullStr Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report
title_full_unstemmed Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report
title_short Paraneoplastic Cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: A case report
title_sort paraneoplastic cushing's syndrome and hypercalcemia arising from metastatic endometrioid endometrial adenocarcinoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620411/
https://www.ncbi.nlm.nih.gov/pubmed/31334321
http://dx.doi.org/10.1016/j.gore.2019.06.005
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