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Aspirin for primary prevention: Is this the end of the road?

Aspirin is one of the oldest and most commonly used cardiovascular drugs. Despite there being high-quality evidence supporting the use of aspirin for patients with known cardiovascular disease, a definitive consensus regarding its use for patients at risk for cardiovascular disease (and without esta...

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Detalles Bibliográficos
Autores principales: Singal, Aayush Kumar, Karthikeyan, Ganesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620426/
https://www.ncbi.nlm.nih.gov/pubmed/31280821
http://dx.doi.org/10.1016/j.ihj.2019.04.001
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author Singal, Aayush Kumar
Karthikeyan, Ganesan
author_facet Singal, Aayush Kumar
Karthikeyan, Ganesan
author_sort Singal, Aayush Kumar
collection PubMed
description Aspirin is one of the oldest and most commonly used cardiovascular drugs. Despite there being high-quality evidence supporting the use of aspirin for patients with known cardiovascular disease, a definitive consensus regarding its use for patients at risk for cardiovascular disease (and without established cardiovascular disease) has never been reached. Many randomized control trials have produced conflicting results, and consequently, society guidelines have issued differring recommendations. Three major trials were published in 2018, which supplement the existing data on aspirin's role in primary prevention and provide further guidance on this contentious issue. This article reviews the history of aspirin through the last two decades, with special emphasis on these new trials.
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spelling pubmed-66204262020-03-01 Aspirin for primary prevention: Is this the end of the road? Singal, Aayush Kumar Karthikeyan, Ganesan Indian Heart J Review Article Aspirin is one of the oldest and most commonly used cardiovascular drugs. Despite there being high-quality evidence supporting the use of aspirin for patients with known cardiovascular disease, a definitive consensus regarding its use for patients at risk for cardiovascular disease (and without established cardiovascular disease) has never been reached. Many randomized control trials have produced conflicting results, and consequently, society guidelines have issued differring recommendations. Three major trials were published in 2018, which supplement the existing data on aspirin's role in primary prevention and provide further guidance on this contentious issue. This article reviews the history of aspirin through the last two decades, with special emphasis on these new trials. Elsevier 2019 2019-05-02 /pmc/articles/PMC6620426/ /pubmed/31280821 http://dx.doi.org/10.1016/j.ihj.2019.04.001 Text en © 2019 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Singal, Aayush Kumar
Karthikeyan, Ganesan
Aspirin for primary prevention: Is this the end of the road?
title Aspirin for primary prevention: Is this the end of the road?
title_full Aspirin for primary prevention: Is this the end of the road?
title_fullStr Aspirin for primary prevention: Is this the end of the road?
title_full_unstemmed Aspirin for primary prevention: Is this the end of the road?
title_short Aspirin for primary prevention: Is this the end of the road?
title_sort aspirin for primary prevention: is this the end of the road?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620426/
https://www.ncbi.nlm.nih.gov/pubmed/31280821
http://dx.doi.org/10.1016/j.ihj.2019.04.001
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