GATA1 gene silencing inhibits invasion, proliferation and migration of cholangiocarcinoma stem cells via disrupting the PI3K/AKT pathway

Background/aims: Intrahepatic cholangiocarcinoma (CCA) is the second most prevalent type primary liver malignancy, accompanied by an increasing global incidence and mortality rate. Research has documented the contribution of the GATA binding protein-1 (GATA1) in the progression of liver cancer. Here...

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Detalles Bibliográficos
Autores principales: Shi, Guang, Zhang, Hong, Yu, Qiong, Hu, Chunmei, Ji, Youbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620705/
https://www.ncbi.nlm.nih.gov/pubmed/31456644
http://dx.doi.org/10.2147/OTT.S198750

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