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The correlation of routine hematological indices with pterygium

PURPOSE: Increased systemic/local inflammation and oxidative stress play a key role in the pathophysiology of pterygium, but there is limited information regarding routine hematological indices’ levels in patients with pterygium. In this study, we aimed to evaluate the levels of complete blood count...

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Autores principales: Kurtul, Bengi Ece, Kabatas, Emrah Utku, Ozates, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620725/
https://www.ncbi.nlm.nih.gov/pubmed/31317124
http://dx.doi.org/10.1177/2515841419848922
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author Kurtul, Bengi Ece
Kabatas, Emrah Utku
Ozates, Serdar
author_facet Kurtul, Bengi Ece
Kabatas, Emrah Utku
Ozates, Serdar
author_sort Kurtul, Bengi Ece
collection PubMed
description PURPOSE: Increased systemic/local inflammation and oxidative stress play a key role in the pathophysiology of pterygium, but there is limited information regarding routine hematological indices’ levels in patients with pterygium. In this study, we aimed to evaluate the levels of complete blood count parameters in patients with pterygium. MATERIAL AND METHOD: In all, 61 patients with pterygium (pterygium group; mean age = 51.4 ± 13.8 years) and 55 healthy individuals (control group; mean age = 50.2 ± 13.1 years) were included in the study. Participants were given routine ophthalmic examinations; complete blood count parameters were assayed. RESULTS: Compared to the control group, red cell distribution width level was significantly higher in patients with pterygium (p = 0.009), but the difference between the groups in terms of the other complete blood count parameters was not statistically significant. However, high-density lipoprotein cholesterol level was significantly lower in the pterygium group than control group (p = 0.015). In the pterygium group, low-density lipoprotein cholesterol levels were lower, but this difference was not statistically significant (p = 0.079). CONCLUSION: Red cell distribution width levels were significantly increased in patients with pterygium. Our data support the idea that inflammation cytokines and oxidative stress may play an important role in the pathogenesis of this disorder.
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spelling pubmed-66207252019-07-17 The correlation of routine hematological indices with pterygium Kurtul, Bengi Ece Kabatas, Emrah Utku Ozates, Serdar Ther Adv Ophthalmol Original Research PURPOSE: Increased systemic/local inflammation and oxidative stress play a key role in the pathophysiology of pterygium, but there is limited information regarding routine hematological indices’ levels in patients with pterygium. In this study, we aimed to evaluate the levels of complete blood count parameters in patients with pterygium. MATERIAL AND METHOD: In all, 61 patients with pterygium (pterygium group; mean age = 51.4 ± 13.8 years) and 55 healthy individuals (control group; mean age = 50.2 ± 13.1 years) were included in the study. Participants were given routine ophthalmic examinations; complete blood count parameters were assayed. RESULTS: Compared to the control group, red cell distribution width level was significantly higher in patients with pterygium (p = 0.009), but the difference between the groups in terms of the other complete blood count parameters was not statistically significant. However, high-density lipoprotein cholesterol level was significantly lower in the pterygium group than control group (p = 0.015). In the pterygium group, low-density lipoprotein cholesterol levels were lower, but this difference was not statistically significant (p = 0.079). CONCLUSION: Red cell distribution width levels were significantly increased in patients with pterygium. Our data support the idea that inflammation cytokines and oxidative stress may play an important role in the pathogenesis of this disorder. SAGE Publications 2019-07-09 /pmc/articles/PMC6620725/ /pubmed/31317124 http://dx.doi.org/10.1177/2515841419848922 Text en © The Author(s), 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Kurtul, Bengi Ece
Kabatas, Emrah Utku
Ozates, Serdar
The correlation of routine hematological indices with pterygium
title The correlation of routine hematological indices with pterygium
title_full The correlation of routine hematological indices with pterygium
title_fullStr The correlation of routine hematological indices with pterygium
title_full_unstemmed The correlation of routine hematological indices with pterygium
title_short The correlation of routine hematological indices with pterygium
title_sort correlation of routine hematological indices with pterygium
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620725/
https://www.ncbi.nlm.nih.gov/pubmed/31317124
http://dx.doi.org/10.1177/2515841419848922
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