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A Prospective, Randomized, Open-Label, Multicenter, Phase III Noninferiority Trial to Compare the Clinical Efficacy of Matrix-Associated Autologous Chondrocyte Implantation With Spheroid Technology Versus Arthroscopic Microfracture for Cartilage Defects of the Knee
BACKGROUND: Autologous chondrocyte implantation (ACI) and microfracture are established treatments for large, full-thickness cartilage defects, but there is still a need to expand the clinical and health economic knowledge of these procedures. PURPOSE: To confirm the noninferiority of ACI compared w...
Autores principales: | Niemeyer, Philipp, Laute, Volker, Zinser, Wolfgang, Becher, Christoph, Kolombe, Thomas, Fay, Jakob, Pietsch, Stefan, Kuźma, Tomasz, Widuchowski, Wojciech, Fickert, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620731/ https://www.ncbi.nlm.nih.gov/pubmed/31317047 http://dx.doi.org/10.1177/2325967119854442 |
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