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Munc13 Is a Molecular Target of Bryostatin 1

[Image: see text] Bryostatin 1 is a natural macrolide shown to improve neuronal connections and enhance memory in mice. Its mechanism of action is largely attributed to the modulation of novel and conventional protein kinase Cs (PKCs) by binding to their regulatory C1 domains. Munc13-1 is a C1 domai...

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Detalles Bibliográficos
Autores principales:	Blanco, Francisco A., Czikora, Agnes, Kedei, Noemi, You, Youngki, Mitchell, Gary A., Pany, Satyabrata, Ghosh, Anamitra, Blumberg, Peter M., Das, Joydip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620733/ https://www.ncbi.nlm.nih.gov/pubmed/31243993 http://dx.doi.org/10.1021/acs.biochem.9b00427

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