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Synthesis and Preclinical Evaluation of the Fibrin-Binding Cyclic Peptide (18)F-iCREKA: Comparison with Its Contrasted Linear Peptide
PURPOSE: Cys-Arg-Glu-Lys-Ala (CREKA) is a pentapeptide which can target fibrin-fibronectin complexes. Our previous study has built a probe called iCREKA which was based on CREKA and has proved the feasibility and specificity of iCREKA by the fluorescence experiment. The purpose of this study is to a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620859/ https://www.ncbi.nlm.nih.gov/pubmed/31346326 http://dx.doi.org/10.1155/2019/6315954 |