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The ESC: The Dangerous By-Product of V(D)J Recombination

V(D)J recombination generates antigen receptor diversity by mixing and matching individual variable (V), diversity (D), and joining (J) gene segments. An obligate by-product of many of these reactions is the excised signal circle (ESC), generated by excision of the DNA from between the gene segments...

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Detalles Bibliográficos
Autores principales:	Smith, Alastair L., Scott, James N. F., Boyes, Joan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620893/ https://www.ncbi.nlm.nih.gov/pubmed/31333681 http://dx.doi.org/10.3389/fimmu.2019.01572

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