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Prolyl 4-Hydroxylase Domain Protein 3-Inhibited Smooth-Muscle-Cell Dedifferentiation Improves Cardiac Perivascular Fibrosis Induced by Obstructive Sleep Apnea

BACKGROUND: Intermittent hypoxia (IH) induced by obstructive sleep apnea (OSA) is a leading factor affecting cardiovascular fibrosis. Under IH condition, smooth muscle cells (SMAs) respond by dedifferentiation, which is associated with vascular remodelling. The expression of prolyl 4-hydroxylase dom...

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Detalles Bibliográficos
Autores principales:	Tong, Jiayi, Yu, Fu-chao, Li, Yang, Wei, Qin, Li, Chen, Zhen, Penghao, Zhang, Guanghao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621170/ https://www.ncbi.nlm.nih.gov/pubmed/31346526 http://dx.doi.org/10.1155/2019/9174218

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