Interferon-Inducible Protein 16 (IFI16) Has a Broad-Spectrum Binding Ability Against ssDNA Targets: An Evolutionary Hypothesis for Antiretroviral Checkpoint

Human endogenous retroviruses (HERVs) are under genomic and epigenetic control but can be expressed in normal tissues, producing RNA transcripts some of which are translated. While it has not been demonstrated experimentally in modern humans, cDNA copies from HERV RNA (namely HERV-K HML-2 or HK2) we...

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Detalles Bibliográficos
Autores principales: Hurst, Tara Patricia, Aswad, Amr, Karamitros, Timokratis, Katzourakis, Aris, Smith, Adrian L., Magiorkinis, Gkikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621918/
https://www.ncbi.nlm.nih.gov/pubmed/31333597
http://dx.doi.org/10.3389/fmicb.2019.01426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621918/
https://www.ncbi.nlm.nih.gov/pubmed/31333597
http://dx.doi.org/10.3389/fmicb.2019.01426

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