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PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α

BACKGROUND: Colorectal cancer (CRC) remains the fourth most common cause of cancer-related mortality worldwide. We aimed to identify key molecules and signalling pathways mediating CRC growth and metastasis. Polypyrimidine tract-binding protein 3 (PTBP3) is a member of PTB family. A prooncogenic rol...

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Detalles Bibliográficos
Autores principales:	Hou, Pingfu, Chen, Fang, Yong, Hongmei, Lin, Tian, Li, Jingjing, Pan, Yu, Jiang, Tao, Li, Minle, Chen, Yansu, Song, Jun, Zheng, Junnian, Bai, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622005/ https://www.ncbi.nlm.nih.gov/pubmed/31291975 http://dx.doi.org/10.1186/s13046-019-1312-y

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