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Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis

CONTEXT: Permanent childhood hearing loss (PCHL) can affect speech, language, and wider outcomes. Adverse effects are mitigated through universal newborn hearing screening (UNHS) and early intervention. OBJECTIVE: We undertook a systematic review and meta-analysis to estimate prevalence of UNHS-dete...

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Autores principales: Butcher, Emma, Dezateux, Carol, Cortina-Borja, Mario, Knowles, Rachel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622528/
https://www.ncbi.nlm.nih.gov/pubmed/31295316
http://dx.doi.org/10.1371/journal.pone.0219600
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author Butcher, Emma
Dezateux, Carol
Cortina-Borja, Mario
Knowles, Rachel L.
author_facet Butcher, Emma
Dezateux, Carol
Cortina-Borja, Mario
Knowles, Rachel L.
author_sort Butcher, Emma
collection PubMed
description CONTEXT: Permanent childhood hearing loss (PCHL) can affect speech, language, and wider outcomes. Adverse effects are mitigated through universal newborn hearing screening (UNHS) and early intervention. OBJECTIVE: We undertook a systematic review and meta-analysis to estimate prevalence of UNHS-detected PCHL (bilateral loss ≥26 dB HL) and its variation by admission to neonatal intensive care unit (NICU). A secondary objective was to report UNHS programme performance (PROSPERO: CRD42016051267). DATA SOURCES: Multiple electronic databases were interrogated in January 2017, with further reports identified from article citations and unpublished literature (November 2017). STUDY SELECTION: UNHS reports from very highly-developed (VHD) countries with relevant prevalence and performance data; no language or date restrictions. DATA EXTRACTION: Three reviewers independently extracted data and assessed quality. RESULTS: We identified 41 eligible reports from 32 study populations (1799863 screened infants) in 6195 non-duplicate references. Pooled UNHS-detected PCHL prevalence was 1.1 per 1000 screened children (95% confidence interval [CI]: 0.9, 1.3; I(2) = 89.2%). This was 6.9 times (95% CI: 3.8, 12.5) higher among those admitted to NICU. Smaller studies were significantly associated with higher prevalences (Egger’s test: p = 0.02). Sensitivity and specificity ranged from 89–100% and 92–100% respectively, positive predictive values from 2–84%, with all negative predictive values 100%. LIMITATIONS: Results are generalisable to VHD countries only. Estimates and inferences were limited by available data. CONCLUSIONS: In VHD countries, 1 per 1000 screened newborns require referral to clinical services for PCHL. Prevalence is higher in those admitted to NICU. Improved reporting would support further examination of screen performance and child demographics.
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spelling pubmed-66225282019-07-25 Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis Butcher, Emma Dezateux, Carol Cortina-Borja, Mario Knowles, Rachel L. PLoS One Research Article CONTEXT: Permanent childhood hearing loss (PCHL) can affect speech, language, and wider outcomes. Adverse effects are mitigated through universal newborn hearing screening (UNHS) and early intervention. OBJECTIVE: We undertook a systematic review and meta-analysis to estimate prevalence of UNHS-detected PCHL (bilateral loss ≥26 dB HL) and its variation by admission to neonatal intensive care unit (NICU). A secondary objective was to report UNHS programme performance (PROSPERO: CRD42016051267). DATA SOURCES: Multiple electronic databases were interrogated in January 2017, with further reports identified from article citations and unpublished literature (November 2017). STUDY SELECTION: UNHS reports from very highly-developed (VHD) countries with relevant prevalence and performance data; no language or date restrictions. DATA EXTRACTION: Three reviewers independently extracted data and assessed quality. RESULTS: We identified 41 eligible reports from 32 study populations (1799863 screened infants) in 6195 non-duplicate references. Pooled UNHS-detected PCHL prevalence was 1.1 per 1000 screened children (95% confidence interval [CI]: 0.9, 1.3; I(2) = 89.2%). This was 6.9 times (95% CI: 3.8, 12.5) higher among those admitted to NICU. Smaller studies were significantly associated with higher prevalences (Egger’s test: p = 0.02). Sensitivity and specificity ranged from 89–100% and 92–100% respectively, positive predictive values from 2–84%, with all negative predictive values 100%. LIMITATIONS: Results are generalisable to VHD countries only. Estimates and inferences were limited by available data. CONCLUSIONS: In VHD countries, 1 per 1000 screened newborns require referral to clinical services for PCHL. Prevalence is higher in those admitted to NICU. Improved reporting would support further examination of screen performance and child demographics. Public Library of Science 2019-07-11 /pmc/articles/PMC6622528/ /pubmed/31295316 http://dx.doi.org/10.1371/journal.pone.0219600 Text en © 2019 Butcher et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Butcher, Emma
Dezateux, Carol
Cortina-Borja, Mario
Knowles, Rachel L.
Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis
title Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis
title_full Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis
title_fullStr Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis
title_full_unstemmed Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis
title_short Prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: Systematic review and meta-analysis
title_sort prevalence of permanent childhood hearing loss detected at the universal newborn hearing screen: systematic review and meta-analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622528/
https://www.ncbi.nlm.nih.gov/pubmed/31295316
http://dx.doi.org/10.1371/journal.pone.0219600
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