Canine IL4-10 fusion protein provides disease modifying activity in a canine model of OA; an exploratory study

OBJECTIVE: An ideal disease modifying osteoarthritis drug (DMOAD) has chondroprotective, anti-inflammatory, and analgesic effects. This study describes the production and characterization of a canine IL4-10 fusion protein (IL4-10 FP) and evaluates its in vivo DMOAD activity in a canine model of oste...

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Detalles Bibliográficos
Autores principales: van Helvoort, E. M., Popov-Celeketic, J., Eijkelkamp, N., Coeleveld, K., Tryfonidou, M. A., Wijne, C. D., Hack, C. E., Lafeber, F. P. J. G., Mastbergen, S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622543/
https://www.ncbi.nlm.nih.gov/pubmed/31295306
http://dx.doi.org/10.1371/journal.pone.0219587

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