Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to L. amazonensis control mediated by P2X7 receptor and leukotriene B(4)

Leishmaniasis is a neglected tropical disease affecting millions of individuals worldwide. P2X7 receptor has been linked to the elimination of Leishmania amazonensis. Biological responses evoked by P2X7 receptor activation have been well-documented, including apoptosis, phagocytosis, cytokine releas...

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Detalles Bibliográficos
Autores principales: Chaves, Mariana M., Sinflorio, Debora A., Thorstenberg, Maria Luiza, Martins, Monique Daiane Andrade, Moreira-Souza, Aline Cristina Abreu, Rangel, Thuany Prado, Silva, Claudia L. M., Bellio, Maria, Canetti, Claudio, Coutinho-Silva, Robson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622556/
https://www.ncbi.nlm.nih.gov/pubmed/31233552
http://dx.doi.org/10.1371/journal.ppat.1007887

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