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HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I

Adult T-cell Leukemia (ATL) is a lymphoproliferative disease of CD4(+) T-cells infected with Human T-cell Leukemia Virus type I (HTLV-1). With the exception of allogeneic hematopoietic stem cell transplantation, there are no effective treatments to cure ATL, and ATL cells often acquire resistance to...

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Detalles Bibliográficos
Autores principales: Rushing, Amanda W., Rushing, Blake, Hoang, Kimson, Sanders, Stephanie V., Péloponèse, Jean-Marie, Polakowski, Nicholas, Lemasson, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623464/
https://www.ncbi.nlm.nih.gov/pubmed/31251786
http://dx.doi.org/10.1371/journal.ppat.1007922

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