The E3 ligase TRIM56 is a host restriction factor of Zika virus and depends on its RNA-binding activity but not miRNA regulation, for antiviral function

Infection by Zika virus (ZIKV) is linked to microcephaly and other neurological disorders, posing a significant health threat. Innate immunity is the first line of defense against invading pathogens, but relatively little is understood regarding host intrinsic mechanisms that guard against ZIKV. Her...

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Detalles Bibliográficos
Autores principales: Yang, Darong, Li, Nan L., Wei, Dahai, Liu, Baoming, Guo, Fang, Elbahesh, Husni, Zhang, Yunzhi, Zhou, Zhi, Chen, Guo-Yun, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623546/
https://www.ncbi.nlm.nih.gov/pubmed/31251739
http://dx.doi.org/10.1371/journal.pntd.0007537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6623546/
https://www.ncbi.nlm.nih.gov/pubmed/31251739
http://dx.doi.org/10.1371/journal.pntd.0007537

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