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Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis
BACKGROUNDS: Recent large-scale genetic studies often involve clustered phenotypes such as repeated measurements. Compared to a series of univariate analyses of single phenotypes, an analysis of clustered phenotypes can be useful for substantially increasing statistical power to detect more genetic...
Autores principales: | Lee, Sungyoung, Kim, Sunmee, Kim, Yongkang, Oh, Bermseok, Hwang, Heungsun, Park, Taesung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624181/ https://www.ncbi.nlm.nih.gov/pubmed/31296220 http://dx.doi.org/10.1186/s12920-019-0517-4 |
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