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Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro
Rotenone (ROT) is an environmental neurotoxin which has been demonstrated to cause characteristic loss of dopamine (DA) neurons in Parkinson’s disease (PD). Icariin (ICA) is a flavonoid glucoside isolated from Herba Epimedii that has been shown to display neuroprotective functions. The present study...
Autores principales: | Zeng, Ru, Zhou, Qian, Zhang, Wei, Fu, Xiaolong, Wu, Qin, Lu, Yuanfu, Shi, Jingshan, Zhou, Shaoyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624214/ https://www.ncbi.nlm.nih.gov/pubmed/31334034 http://dx.doi.org/10.1016/j.toxrep.2019.06.014 |
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