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Icariin-mediated activation of autophagy confers protective effect on rotenone induced neurotoxicity in vivo and in vitro

Rotenone (ROT) is an environmental neurotoxin which has been demonstrated to cause characteristic loss of dopamine (DA) neurons in Parkinson’s disease (PD). Icariin (ICA) is a flavonoid glucoside isolated from Herba Epimedii that has been shown to display neuroprotective functions. The present study...

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Detalles Bibliográficos
Autores principales: Zeng, Ru, Zhou, Qian, Zhang, Wei, Fu, Xiaolong, Wu, Qin, Lu, Yuanfu, Shi, Jingshan, Zhou, Shaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624214/
https://www.ncbi.nlm.nih.gov/pubmed/31334034
http://dx.doi.org/10.1016/j.toxrep.2019.06.014

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