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Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

Lipid-induced toxicity is part of several human diseases, but the mechanisms involved are not fully understood. Fatty liver is characterized by the expression of different growth and tissue factors. The neurotrophin, nerve growth factor (NGF) and its pro-form, pro-NGF, are present in fatty liver tog...

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Detalles Bibliográficos
Autores principales: Pham, Dan Duc, Bruelle, Céline, Thi Do, Hai, Pajanoja, Ceren, Jin, Congyu, Srinivasan, Vignesh, Olkkonen, Vesa M., Eriksson, Ove, Jauhiainen, Matti, Lalowski, Maciej, Lindholm, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624261/
https://www.ncbi.nlm.nih.gov/pubmed/31296846
http://dx.doi.org/10.1038/s41419-019-1758-z