Cargando…

Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study

Pre-symptomatic screening of genetic alterations might help identify subpopulations of individuals that could enter into early access prevention programs. Since liquid biopsy is minimally invasive it can be used for longitudinal studies in healthy volunteers to monitor events of progression from nor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alborelli, Ilaria, Generali, Daniele, Jermann, Philip, Cappelletti, Maria Rosa, Ferrero, Giuseppina, Scaggiante, Bruna, Bortul, Marina, Zanconati, Fabrizio, Nicolet, Stefan, Haegele, Jasmin, Bubendorf, Lukas, Aceto, Nicola, Scaltriti, Maurizio, Mucci, Giuseppe, Quagliata, Luca, Novelli, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624284/ https://www.ncbi.nlm.nih.gov/pubmed/31296838 http://dx.doi.org/10.1038/s41419-019-1770-3

Ejemplares similares

Current status of PI3K-mTOR inhibition in hormone-receptor positive, HER2-negative breast cancer
por: Sobhani, Navid, et al.
Publicado: (2018)

Next-Generation Sequencing and Triple-Negative Breast Cancer: Insights and Applications
por: Tierno, Domenico, et al.
Publicado: (2023)

A Case–Control Study by ddPCR of ALU 260/111 and LINE-1 266/97 Copy Number Ratio in Circulating Cell-Free DNA in Plasma Revealed LINE-1 266/97 as a Potential Biomarker for Early Breast Cancer Detection
por: Bortul, Marina, et al.
Publicado: (2023)

Tumor mutational burden assessed by targeted NGS predicts clinical benefit from immune checkpoint inhibitors in non‐small cell lung cancer
por: Alborelli, Ilaria, et al.
Publicado: (2019)

An Overview of Circulating Cell-Free Nucleic Acids in Diagnosis and Prognosis of Triple-Negative Breast Cancer
por: Tierno, Domenico, et al.
Publicado: (2023)

Circulating cell-free nucleic acids as prognostic and therapy predictive tools for metastatic castrate-resistant prostate cancer
por: Sobhani, Navid, et al.
Publicado: (2020)

Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations
por: Castro-Giner, Francesc, et al.
Publicado: (2018)

Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer
por: Sobhani, Navid, et al.
Publicado: (2018)

Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals
por: Bosutti, Alessandra, et al.
Publicado: (2016)

Elevated levels of eEF1A2 protein expression in triple negative breast cancer relate with poor prognosis
por: Giudici, Fabiola, et al.
Publicado: (2019)

Correction: Elevated levels of eEF1A2 protein expression in triple negative breast cancer relate with poor prognosis
por: Giudici, Fabiola, et al.
Publicado: (2019)

Impact of psychosocial, behavioral and lifestyle factors on subjective cognitive complaints and perceived quality of life in a large cohort of Italian breast cancer patients
por: West, Thomas, et al.
Publicado: (2022)

Comparison between male and female breast cancer survival using propensity score matching analysis
por: Scomersi, Serena, et al.
Publicado: (2021)

Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics
por: Haefliger, Simon, et al.
Publicado: (2023)

Technical aspects, R&D and Proof-of-Principle
por: Dutheil, Yann
Publicado: (2020)

High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1–actin Complex as a New Potential Target for Therapy
por: Bosutti, Alessandra, et al.
Publicado: (2022)

Cyclin dependent kinase 4 and 6 inhibitors as novel therapeutic agents for targeted treatment of malignant mesothelioma
por: Sobhani, Navid, et al.
Publicado: (2017)

Tumor Type Agnostic Therapy Carrying BRAF Mutation: Case Reports and Review of Literature
por: Bernocchi, Ottavia, et al.
Publicado: (2021)

Only EBUS-Guided Mediastinal Lymph Node Cryobiopsy Enabled Immunotherapy in a Patient with Non-Small Cell Lung Cancer
por: Hetzel, Jürgen, et al.
Publicado: (2023)

Xenograft Zebrafish Models for the Development of Novel Anti-Hepatocellular Carcinoma Molecules
por: Tonon, Federica, et al.
Publicado: (2021)

Emotional intelligence and emotion information processing: Proof of concept of a test measuring accuracy in discriminating emotions
por: Gillioz, Christelle, et al.
Publicado: (2023)

Technical Note: Proof of concept for radiomics‐based quality assurance for computed tomography
por: Branco, Luciano R. F., et al.
Publicado: (2019)

T cell subtype profiling measures exhaustion and predicts anti-PD-1 response
por: Schillebeeckx, Ian, et al.
Publicado: (2022)

Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression
por: Scaggiante, B, et al.
Publicado: (2012)

Technical Note: First Use of Endonasal Confocal Laser Endomicroscopy – Feasibility and Proof of Concept
por: Wenda, Nina, et al.
Publicado: (2021)

Association between benign thyroid disease and breast cancer: a single center experience
por: Dobrinja, Chiara, et al.
Publicado: (2019)

Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment
por: Campaner, Elena, et al.
Publicado: (2020)

Voyage dans un observatoire
por: Jermann, Iris
Publicado: (2017)

Circulating tumor cells correlate with patterns of recurrence in patients with hormone-sensitive prostate cancer
por: Roviello, Giandomenico, et al.
Publicado: (2017)

Loss of HER2 in breast cancer: biological mechanisms and technical pitfalls
por: Morganti, Stefania, et al.
Publicado: (2022)

Computational reactive–diffusive modeling for stratification and prognosis determination of patients with breast cancer receiving Olaparib
por: Schettini, Francesco, et al.
Publicado: (2023)

Proof-of-Principle of a Cherenkov-Tag Detector Prototype
por: Gallo, Giuseppe, et al.
Publicado: (2020)

Technical Note: A respiratory monitoring and processing system based on computer vision: prototype and proof of principle
por: Leduc, Nicolas, et al.
Publicado: (2016)

Technical Note: Nuclear imaging with an x‐ray flat panel detector: A proof‐of‐concept study
por: Dietze, Martijn M. A., et al.
Publicado: (2020)

Advanced Techniques for Endoscopic Intracerebral Hemorrhage Evacuation: A Technical Report With Case Examples
por: Rothrock, Robert J, et al.
Publicado: (2020)

Application of Next Generation Sequencing for personalized medicine for sudden cardiac death
por: Morini, Elena, et al.
Publicado: (2015)

Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging—A Proof-of-Concept Study
por: Wegner, Franz, et al.
Publicado: (2022)

Pharmacological and Nutraceutical Activation of Rejuvenation, Geroprotection and Cytoprotection: Proofs of Concept
por: Lizard, Gérard, et al.
Publicado: (2022)

Nano-MnO(2) Decoration of TiO(2) Microparticles to Promote Gaseous Ethanol Visible Photoremoval
por: Stucchi, Marta, et al.
Publicado: (2018)

Would the combination of everolimus with endocrine-therapy help in FGFR2 positive serous endometrial cancer?
por: Cappelletti, Maria Rosa, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2mpcfd8ekaav60vle5bii02ve1