NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

Faithful transcription initiation is critical for accurate gene expression, yet the mechanisms underlying specific transcription start site (TSS) selection in mammals remain unclear. Here, we show that the histone-fold domain protein NF-Y, a ubiquitously expressed transcription factor, controls the...

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Detalles Bibliográficos
Autores principales: Oldfield, Andrew J., Henriques, Telmo, Kumar, Dhirendra, Burkholder, Adam B., Cinghu, Senthilkumar, Paulet, Damien, Bennett, Brian D., Yang, Pengyi, Scruggs, Benjamin S., Lavender, Christopher A., Rivals, Eric, Adelman, Karen, Jothi, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624317/
https://www.ncbi.nlm.nih.gov/pubmed/31296853
http://dx.doi.org/10.1038/s41467-019-10905-7

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