Expression of a CARD Slows the Retinal Degeneration of a Geographic Atrophy Mouse Model

Age-related macular degeneration (AMD) has been linked to oxidative damage and para-inflammation, an activation of inflammasome signaling in the retinal pigment epithelium (RPE) and the underlying choriocapillaris. Herein, we tested the efficacy of a gene-delivered caspase-1 inhibitor in controlling...

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Detalles Bibliográficos
Autores principales: Young, Brianna M., Jones, Kyle, Massengill, Michael T., Walsh, Erin, Li, Hong, Lewin, Alfred S., Ildefonso, Cristhian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624323/
https://www.ncbi.nlm.nih.gov/pubmed/31334304
http://dx.doi.org/10.1016/j.omtm.2019.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624323/
https://www.ncbi.nlm.nih.gov/pubmed/31334304
http://dx.doi.org/10.1016/j.omtm.2019.06.001

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