Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

The importance of axial chirality in enantioselective synthesis has been widely recognized for decades. The practical access to certain structures such as biaryl amino phenols known as NOBINs in enantiopure form, however, still remains a challenge. In drug delivery, the incorporation of axially chir...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Shenci, Ng, Shawn Voon Hwee, Lovato, Kaitlyn, Ong, Jun-Yang, Poh, Si Bei, Ng, Xiao Qian, Kürti, László, Zhao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624369/
https://www.ncbi.nlm.nih.gov/pubmed/31296858
http://dx.doi.org/10.1038/s41467-019-10940-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624369/
https://www.ncbi.nlm.nih.gov/pubmed/31296858
http://dx.doi.org/10.1038/s41467-019-10940-4

Ejemplares similares