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Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
The importance of axial chirality in enantioselective synthesis has been widely recognized for decades. The practical access to certain structures such as biaryl amino phenols known as NOBINs in enantiopure form, however, still remains a challenge. In drug delivery, the incorporation of axially chir...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624369/ https://www.ncbi.nlm.nih.gov/pubmed/31296858 http://dx.doi.org/10.1038/s41467-019-10940-4 |