Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia

Intermittent stress disrupts the circadian rhythm in clock genes such as Per2 only in peripheral organs without any effect on the central circadian clock in the suprachiasmatic nucleus. Here, the effect of restraint stress (RS) on circadian bladder function was investigated based on urination behavi...

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Detalles Bibliográficos
Autores principales: Ihara, Tatsuya, Nakamura, Yuki, Mitsui, Takahiko, Tsuchiya, Sachiko, Kanda, Mie, Kira, Satoru, Nakagomi, Hiroshi, Sawada, Norifumi, Kamiyama, Manabu, Shigetomi, Eiji, Shinozaki, Youichi, Yoshiyama, Mitsuharu, Nakao, Atsuhito, Koizumi, Schuichi, Takeda, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624370/
https://www.ncbi.nlm.nih.gov/pubmed/31296902
http://dx.doi.org/10.1038/s41598-019-46517-w

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