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Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity
Lamin A is a nuclear intermediate filament protein critical for nuclear architecture and mechanics and mutated in a wide range of human diseases. Yet little is known about the molecular architecture of lamins and mechanisms of their assembly. Here we use SILAC cross-linking mass spectrometry to dete...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624373/ https://www.ncbi.nlm.nih.gov/pubmed/31296869 http://dx.doi.org/10.1038/s41467-019-11063-6 |