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Pharmacodynamics of rituximab on B lymphocytes in paediatric patients with autoimmune diseases

AIMS: Rituximab is a chimeric IgG‐1 monoclonal antibody that depletes B cells, aiding in the treatment of several conditions including autoimmune diseases. It is not licensed for use in children. This study aimed to quantify the B cell‐related pharmacodynamics of rituximab in children with autoimmun...

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Detalles Bibliográficos
Autores principales:	Pan, Shan, Yu, Huixin, Surti, Ayesha, Cheng, Iek, Marks, Stephen D., Brogan, Paul A., Eleftheriou, Despina, Standing, Joseph F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624401/ https://www.ncbi.nlm.nih.gov/pubmed/31026092 http://dx.doi.org/10.1111/bcp.13970

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