Cargando…

Pharmacokinetics of Intranasally Administered Dexmedetomidine in Chinese Children

Background: Intranasal application is a comfortable, effective, nearly non-invasive, and easy route of administration in children. To date, there is, however, only one pharmacokinetic study on intranasal dexmedetomidine in pediatric populations and none in Chinese children available. Therefore, this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Cheng-Yu, Ihmsen, Harald, Hu, Zhi-Yan, Chen, Jia, Ye, Xue-Fei, Chen, Fang, Lu, Yi, Schüttler, Jürgen, Lian, Qing-Quan, Liu, Hua-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624439/ https://www.ncbi.nlm.nih.gov/pubmed/31333469 http://dx.doi.org/10.3389/fphar.2019.00756

Ejemplares similares

Safety and Pharmacokinetics of Intranasally Administered Heparin
por: Harris, Hannah M., et al.
Publicado: (2022)

Safety and Pharmacokinetics of Intranasally Administered Heparin
por: Harris, Hannah M., et al.
Publicado: (2022)

Comparison of the Effects of Oral Midazolam and Intranasal Dexmedetomidine on Preoperative Sedation and Anesthesia Induction in Children Undergoing Surgeries
por: Cai, Yu-Hang, et al.
Publicado: (2021)

Intranasally Administered Adjunctive Dexmedetomidine Reduces Perioperative Anesthetic Requirements in General Anesthesia
por: Wu, Xiang, et al.
Publicado: (2016)

Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ(25–35)
por: Lee, Youn Young, et al.
Publicado: (2023)

Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS
por: Wehrfritz, Andreas, et al.
Publicado: (2022)

A Comparison of Intranasal Dexmedetomidine, Esketamine or a Dexmedetomidine-Esketamine Combination for Induction of Anaesthesia in Children: A Randomized Controlled Double-Blind Trial
por: Lu, Xinlei, et al.
Publicado: (2022)

Intranasal dexmedetomidine improves postoperative sleep quality in older patients with chronic insomnia: a randomized double-blind controlled trial
por: Wu, Jinghan, et al.
Publicado: (2023)

Intranasal dexmedetomidine is an effective sedative agent for electroencephalography in children
por: Chen, Hang, et al.
Publicado: (2020)

Pharmacokinetic Properties of Three Forms of Vaginal Progesterone Administered in Either Single Or Multiple Dose Regimen in Healthy Post-menopausal Chinese Women
por: Wu, Guolan, et al.
Publicado: (2017)

Population Pharmacokinetics of Vancomycin in Chinese ICU Neonates: Initial Dosage Recommendations
por: Li, Zhi-ling, et al.
Publicado: (2018)

Pharmacokinetics, Safety and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects
por: Yang, Haijing, et al.
Publicado: (2022)

Pharmacokinetics of Orally Administered Oseltamivir in Healthy Obese and Nonobese Thai Subjects
por: Jittamala, Podjanee, et al.
Publicado: (2014)

The pharmacokinetic study of tacrolimus and Wuzhi capsule in Chinese liver transplant patients
por: Qu, Jinlong, et al.
Publicado: (2022)

Pharmacokinetics and pharmacodynamics of intranasal and intramuscular administration of naloxone in working dogs administered fentanyl
por: Barr, Ciara A., et al.
Publicado: (2023)

Parental presence and intranasal dexmedetomidine for the prevention of anxiety during anesthesia induction in children undergoing tonsillectomy and/or adenoidectomy surgery: A randomized controlled trial
por: Yao, Jing, et al.
Publicado: (2022)

Antibody Format and Serum Disposition Govern Ocular Pharmacokinetics of Intravenously Administered Protein Therapeutics
por: Shivva, Vittal, et al.
Publicado: (2021)

Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs
por: Vlerick, Lise, et al.
Publicado: (2020)

Intranasal dexmedetomidine and intranasal ketamine association allows shorter induction time for pediatric sedation compared to intranasal dexmedetomidine and oral midazolam
por: Cossovel, Francesca, et al.
Publicado: (2022)

The Protective Effect and Mechanism of Dexmedetomidine on Diabetic Peripheral Neuropathy in Rats
por: Zhang, Yan-zhuo, et al.
Publicado: (2020)

Safety and Pharmacokinetics of the Aminomethylcycline Antibiotic Omadacycline Administered to Healthy Subjects in Oral Multiple-Dose Regimens
por: Bundrant, Lu Ann, et al.
Publicado: (2018)

Pharmacokinetics of single dose sildenafil orally administered in canine models of chronic embolic pulmonary hypertension
por: AKABANE, Ryota, et al.
Publicado: (2020)

Differences in the pharmacokinetics and steady-state blood concentrations of orally administered lenvatinib in adult and juvenile rats
por: Du, Xiaoyue, et al.
Publicado: (2023)

Pharmacokinetics and safety of the two oral cefaclor formulations in healthy chinese subjects in the fasting and postprandial states
por: Qu, Xinyao, et al.
Publicado: (2022)

Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder
por: Jin, Zi-bin, et al.
Publicado: (2022)

Pharmacokinetics and Pharmacodynamics of Butorphanol and Dexmedetomidine after Intranasal Administration in Broiler Chickens (Gallus gallus domesticus)
por: Sha, Jin, et al.
Publicado: (2022)

Population Pharmacokinetics of Cyclosporine in Chinese Pediatric Patients With Acquired Aplastic Anemia
por: Gao, Xuan, et al.
Publicado: (2022)

Safety, Pharmacokinetics/Pharmacodynamics, and Absolute Bioavailability of Dexmedetomidine Hydrochloride Nasal Spray in Healthy Subjects: A Randomized, Parallel, Escalating Dose Study
por: Kuang, Yun, et al.
Publicado: (2022)

Population Pharmacokinetics of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia
por: Gao, Xuan, et al.
Publicado: (2021)

A phase 1 study of dimdazenil to evaluate the pharmacokinetics, food effect and safety in Chinese healthy subjects
por: Wang, Fei, et al.
Publicado: (2023)

Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of CMAB807, a New Denosumab Biosimilar, in Healthy Chinese Subjects
por: Chen, Hanjing, et al.
Publicado: (2022)

Comparative Study of Intranasal Dexmedetomidine Versus Intranasal Ketamine as Premedicant in Children
por: Arun, Nidhi, et al.
Publicado: (2022)

Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients
por: Li, Xiao-lin, et al.
Publicado: (2022)

Mechanism and Basis of Traditional Chinese Medicine Against Obesity: Prevention and Treatment Strategies
por: Zhang, Chang-hua, et al.
Publicado: (2021)

Effects of Comedication and Genetic Factors on the Population Pharmacokinetics of Lamotrigine: A Prospective Analysis in Chinese Patients With Epilepsy
por: Wang, Zhan-zhang, et al.
Publicado: (2019)

Effect of dexmedetomidine on liver transplantation: a meta-analysis
por: Jia, Degong, et al.
Publicado: (2023)

Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers
por: Li, Jiayu, et al.
Publicado: (2023)

The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness
por: Yuan, Hong-Kai, et al.
Publicado: (2022)

Intranasal sufentanil combined with intranasal dexmedetomidine: A promising method for non-anesthesiologist sedation during endoscopic ultrasonography
por: Wang, Yong, et al.
Publicado: (2022)

Population Pharmacokinetics and Pharmacodynamics of Isoniazid and its Metabolite Acetylisoniazid in Chinese Population
por: Chen, Bing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_phcl8i6bg805555ou7go05lool