Brain histamine H(1) receptor occupancy after oral administration of desloratadine and loratadine

Some histamine H(1) receptor (H(1)R) antagonists induce adverse sedative reactions caused by blockade of histamine transmission in the brain. Desloratadine is a second‐generation antihistamine for treatment of allergic disorders. Its binding to brain H(1)Rs, which is the basis of sedative property o...

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Detalles Bibliográficos
Autores principales: Nakamura, Tadaho, Hiraoka, Kotaro, Harada, Ryuichi, Matsuzawa, Takuro, Ishikawa, Yoichi, Funaki, Yoshihito, Yoshikawa, Takeo, Tashiro, Manabu, Yanai, Kazuhiko, Okamura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624455/
https://www.ncbi.nlm.nih.gov/pubmed/31338198
http://dx.doi.org/10.1002/prp2.499

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