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Analyzing complex single molecule emission patterns with deep learning
A fluorescent emitter simultaneously transmits its identity, location, and cellular context through its emission pattern. We developed smNet, a deep neural network for multiplexed single-molecule analysis to enable retrieving such information with high accuracy. We demonstrate that smNet can extract...
Autores principales: | Zhang, Peiyi, Liu, Sheng, Chaurasia, Abhishek, Ma, Donghan, Mlodzianoski, Michael J., Culurciello, Eugenio, Huang, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624853/ https://www.ncbi.nlm.nih.gov/pubmed/30377349 http://dx.doi.org/10.1038/s41592-018-0153-5 |
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