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The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells

BACKGROUND: The molecular mechanisms underlying cervical cancer require elucidation to identify novel therapeutic targets. Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) is a multifunctional apurinic/apyrimidinic (AP) endonuclease that influences the transcription of many cancer-related genes...

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Detalles Bibliográficos
Autores principales:	Sun, Yi, Feng, Yun, Zhang, Guiqian, Xu, Ya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624912/ https://www.ncbi.nlm.nih.gov/pubmed/31320936 http://dx.doi.org/10.1177/1758835919855859

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