A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice

BACKGROUND: Given the central importance of anti-malarial drugs in the treatment of malaria, there is a need to understand the effect of Plasmodium infection on the broad spectrum of drug metabolizing enzymes. Previous studies have shown reduced clearance of quinine, a treatment for Plasmodium infec...

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Detalles Bibliográficos
Autores principales: Mimche, Sylvie M., Lee, Choon-myung, Liu, Ken H., Mimche, Patrice N., Harvey, R. Donald, Murphy, Thomas J., Nyagode, Beatrice A., Jones, Dean P., Lamb, Tracey J., Morgan, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624958/
https://www.ncbi.nlm.nih.gov/pubmed/31299982
http://dx.doi.org/10.1186/s12936-019-2860-5

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