Genomic landscape and its correlations with tumor mutational burden, PD-L1 expression, and immune cells infiltration in Chinese lung squamous cell carcinoma

INTRODUCTION: To depict the genomic landscape of Chinese early-stage lung squamous cell carcinoma (LUSC) and investigate its correlation with tumor mutation burden (TMB), PD-L1 expression, and immune infiltrates. METHODS: Whole-exome sequencing was performed on 189 surgically resected LUSC. TMB was...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Shi, Jinpeng, Dong, Zhengwei, Hou, Likun, Zhao, Chao, Li, Xuefei, Mao, Beibei, Zhu, Wei, Guo, Xianchao, Zhang, Henghui, He, Ji, Chen, Xiaoxia, Su, Chunxia, Ren, Shengxiang, Wu, Chunyan, Zhou, Caicun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625041/
https://www.ncbi.nlm.nih.gov/pubmed/31299995
http://dx.doi.org/10.1186/s13045-019-0762-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625041/
https://www.ncbi.nlm.nih.gov/pubmed/31299995
http://dx.doi.org/10.1186/s13045-019-0762-1

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