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Kidney and cystic volume imaging for disease presentation and progression in the cat autosomal dominant polycystic kidney disease large animal model

BACKGROUND: Approximately 30% of Persian cats have a c.10063C > A variant in polycystin 1 (PKD1) homolog causing autosomal dominant polycystic kidney disease (ADPKD). The variant is lethal in utero when in the homozygous state and is the only ADPKD variant known in cats. Affected cats have a wide...

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Detalles Bibliográficos
Autores principales: Yu, Yoshihiko, Shumway, Kate L., Matheson, Jodi S., Edwards, Marie E., Kline, Timothy L., Lyons, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625046/
https://www.ncbi.nlm.nih.gov/pubmed/31299928
http://dx.doi.org/10.1186/s12882-019-1448-1