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High glucose microenvironment accelerates tumor growth via SREBP1-autophagy axis in pancreatic cancer
BACKGROUND: Diabetes is recognized to be a risk factor of pancreatic cancer, but the mechanism has not been fully elucidated. Sterol regulatory element binding protein 1 (SREBP1) is an important transcription factor involved in both lipid metabolism and tumor progression. However, the relationship b...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625066/ https://www.ncbi.nlm.nih.gov/pubmed/31296258 http://dx.doi.org/10.1186/s13046-019-1288-7 |