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High glucose microenvironment accelerates tumor growth via SREBP1-autophagy axis in pancreatic cancer

BACKGROUND: Diabetes is recognized to be a risk factor of pancreatic cancer, but the mechanism has not been fully elucidated. Sterol regulatory element binding protein 1 (SREBP1) is an important transcription factor involved in both lipid metabolism and tumor progression. However, the relationship b...

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Detalles Bibliográficos
Autores principales:	Zhou, Cancan, Qian, Weikun, Li, Jie, Ma, Jiguang, Chen, Xin, Jiang, Zhengdong, Cheng, Liang, Duan, Wanxing, Wang, Zheng, Wu, Zheng, Ma, Qingyong, Li, Xuqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625066/ https://www.ncbi.nlm.nih.gov/pubmed/31296258 http://dx.doi.org/10.1186/s13046-019-1288-7

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