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Tumor-released autophagosomes induces CD4(+) T cell-mediated immunosuppression via a TLR2–IL-6 cascade
BACKGROUND: CD4(+) T cells are critical effectors of anti-tumor immunity, but how tumor cells influence CD4(+) T cell effector function is not fully understood. Tumor cell-released autophagosomes (TRAPs) are being recognized as critical modulators of host anti-tumor immunity during tumor progression...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625067/ https://www.ncbi.nlm.nih.gov/pubmed/31300052 http://dx.doi.org/10.1186/s40425-019-0646-5 |