Tumor-released autophagosomes induces CD4(+) T cell-mediated immunosuppression via a TLR2–IL-6 cascade

BACKGROUND: CD4(+) T cells are critical effectors of anti-tumor immunity, but how tumor cells influence CD4(+) T cell effector function is not fully understood. Tumor cell-released autophagosomes (TRAPs) are being recognized as critical modulators of host anti-tumor immunity during tumor progression...

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Detalles Bibliográficos
Autores principales: Chen, Yong-Qiang, Li, Peng-Cheng, Pan, Ning, Gao, Rong, Wen, Zhi-Fa, Zhang, Tian-Yu, Huang, Fang, Wu, Fang-Yuan, Ou, Xi-Long, Zhang, Jin-Ping, Zhu, Xue-Jun, Hu, Hong-Ming, Chen, Kang, Cai, Yun-Lang, Wang, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625067/
https://www.ncbi.nlm.nih.gov/pubmed/31300052
http://dx.doi.org/10.1186/s40425-019-0646-5

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