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TET2 missense variants in human neoplasia. A proposal of structural and functional classification

BACKGROUND: The human TET2 gene plays a pivotal role in the epigenetic regulation of normal and malignant hematopoiesis. Somatic TET2 mutations have been repeatedly identified in age‐related clonal hematopoiesis and in myeloid neoplasms ranging from acute myeloid leukemia (AML) to myeloproliferative...

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Detalles Bibliográficos
Autores principales:	Bussaglia, Elena, Antón, Rosa, Nomdedéu, Josep F., Fuentes‐Prior, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625141/ https://www.ncbi.nlm.nih.gov/pubmed/31187595 http://dx.doi.org/10.1002/mgg3.772

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