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Reduced ribosomal RNA expression and unchanged ribosomal DNA promoter methylation in oral squamous cell carcinoma

BACKGROUND: Ribosomal RNA (rRNA) consists of four non‐coding RNAs, the 28S, 5.8S, 18S, and 5S rRNA. Abnormal expression of rRNA has been found in multiple tumors, and the methylation of rDNA promoter may affect rRNA expression as an epigenetic regulatory mechanism. Oral squamous cell carcinoma (OSCC...

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Detalles Bibliográficos
Autores principales:	Ha, Shanshan, Zhou, Hong, Gautam, Mayank, Song, Yaling, Wang, Changning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625366/ https://www.ncbi.nlm.nih.gov/pubmed/31169368 http://dx.doi.org/10.1002/mgg3.783

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