Cargando…

Artesunate exerts protective effects against ulcerative colitis via suppressing Toll-like receptor 4 and its downstream nuclear factor-κB signaling pathways

Artesunate (ART) is a semi-synthetic derivative of artemisinin used in the treatment of patients with malaria, which has also been reported to have immunoregulatory, anticancer and anti-inflammatory properties. The aim of the present study was to investigate the possible beneficial effects of ART on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yu-Xuan, Zhang, Xiao-Qi, Yu, Cheng-Gong, Huang, Shu-Ling, Xie, Ying, Dou, Xiao-Tan, Liu, Wen-Jia, Zou, Xiao-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625425/ https://www.ncbi.nlm.nih.gov/pubmed/31173225 http://dx.doi.org/10.3892/mmr.2019.10345

Ejemplares similares

Artesunate alleviates the inflammatory response of ulcerative colitis by regulating the expression of miR-155
por: Yang, Zhao-Bin, et al.
Publicado: (2021)

Jianpi Qingchang decoction alleviates ulcerative colitis by inhibiting nuclear factor-κB activation
por: Zheng, Lie, et al.
Publicado: (2017)

N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways
por: Huang, Li-Jun, et al.
Publicado: (2022)

Histological evaluation in ulcerative colitis
por: DeRoche, Tom C., et al.
Publicado: (2014)

Expression of Toll-like receptors in the mucosa of patients with ulcerative colitis
por: FAN, YUJING, et al.
Publicado: (2015)

LRCH1 suppresses migration of CD4(+) T cells and refers to disease activity in ulcerative colitis
por: Wang, Yibo, et al.
Publicado: (2020)

Toll-like receptor downstream signaling
por: Kawai, Taro, et al.
Publicado: (2005)

Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway
por: Chen, Xiao, et al.
Publicado: (2017)

Atractylenolide-I Suppresses Tumorigenesis of Breast Cancer by Inhibiting Toll-Like Receptor 4-Mediated Nuclear Factor-κB Signaling Pathway
por: Long, Fangyi, et al.
Publicado: (2020)

Akkermansia muciniphila Exerts Strain-Specific Effects on DSS-Induced Ulcerative Colitis in Mice
por: Liu, Qing, et al.
Publicado: (2021)

Albumin as a prognostic marker for ulcerative colitis
por: Khan, Nabeel, et al.
Publicado: (2017)

Deoxyschizandrin Suppresses DSS-Induced Ulcerative Colitis in Mice
por: Zhang, Wen-feng, et al.
Publicado: (2016)

Smoldering Multiple Myeloma Arising in Ulcerative Colitis
por: Yang, Xue, et al.
Publicado: (2018)

Pinocembrin alleviates ulcerative colitis in mice via regulating gut microbiota, suppressing TLR4/MD2/NF-κB pathway and promoting intestinal barrier
por: Yue, Bei, et al.
Publicado: (2020)

Alhagi pseudalhagi Extract Exerts Protective Effects Against Intestinal Inflammation in Ulcerative Colitis by Affecting TLR(4)-Dependent NF-κB Signaling Pathways
por: Xu, Xiaoqin, et al.
Publicado: (2021)

Artesunate Exerts a Direct Effect on Endothelial Cell Activation and NF-κB Translocation in a Mechanism Independent of Plasmodium Killing
por: Souza, Mariana C., et al.
Publicado: (2012)

Zoledronic acid inhibits osteoclastogenesis and bone resorptive function by suppressing RANKL-mediated NF-κB and JNK and their downstream signalling pathways
por: Huang, Xiao-Lin, et al.
Publicado: (2022)

Anti-Inflammatory Effects of Huangqin Decoction on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through Regulation of the Gut Microbiota and Suppression of the Ras-PI3K-Akt-HIF-1α and NF-κB Pathways
por: Li, Min-yao, et al.
Publicado: (2020)

The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice
por: Yin, Shaojie, et al.
Publicado: (2021)

Delayed Resolution of Acute Inflammation in Ulcerative Colitis Is Associated with Elevated Cytokine Release Downstream of TLR4
por: Rahman, Farooq Z., et al.
Publicado: (2010)

Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression
por: Zhang, Xu, et al.
Publicado: (2020)

The Protection of Crocin Against Ulcerative Colitis and Colorectal Cancer via Suppression of NF-κB-Mediated Inflammation
por: Teng, Shanshan, et al.
Publicado: (2021)

Artesunate suppresses Th17 response via inhibiting IRF4-mediated glycolysis and ameliorates Sjog̈ren’s syndrome
por: Xiao, Fan, et al.
Publicado: (2022)

Jatrorrhizine alleviates ulcerative colitis via regulating gut microbiota and NOS2 expression
por: Zhang, Jia Ling, et al.
Publicado: (2022)

Targeting ulcerative colitis by suppressing glucose uptake with ritonavir
por: Jodeleit, Henrika, et al.
Publicado: (2018)

Artesunate attenuates LPS-induced osteoclastogenesis by suppressing TLR4/TRAF6 and PLCγ1-Ca(2+)-NFATc1 signaling pathway
por: Zeng, Xiang-zhou, et al.
Publicado: (2019)

Comparing the clinical application values of the Degree of Ulcerative Colitis Burden of Luminal Inflammation (DUBLIN) score and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) in patients with ulcerative colitis
por: Zhang, Xiao-Fei, et al.
Publicado: (2021)

Garidisan: Improving the Quality of Ulcer Healing in Rats with Ulcerative Colitis
por: Wang, Lin, et al.
Publicado: (2017)

The oral bacterial microbiota facilitates the stratification for ulcerative colitis patients with oral ulcers
por: Xu, Jun, et al.
Publicado: (2023)

Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway
por: Liu, Qi, et al.
Publicado: (2020)

Transcript levels of Toll-Like receptors 5, 8 and 9 correlate with inflammatory activity in Ulcerative Colitis
por: Sánchez-Muñoz, Fausto, et al.
Publicado: (2011)

Sevoflurane Inhibits Nuclear Factor-κB Activation in Lipopolysaccharide-Induced Acute Inflammatory Lung Injury via Toll-Like Receptor 4 Signaling
por: Sun, Xi Jia, et al.
Publicado: (2015)

Gut mucosal virome alterations in ulcerative colitis
por: Zuo, Tao, et al.
Publicado: (2019)

Protective effect of Gloeostereum incarnatum on ulcerative colitis via modulation of Nrf2/NF-κB signaling in C57BL/6 mice
por: Li, Xiao, et al.
Publicado: (2020)

Effects of ω-3 fatty acids on toll-like receptor 4 and nuclear factor-κB p56 in lungs of rats with severe acute pancreatitis
por: Wang, Bin, et al.
Publicado: (2016)

Firstborn microcrystallization method to prepare nanocapsules containing artesunate
por: Xiao, Xin-Cai, et al.
Publicado: (2010)

SUPPRESSION OF GHRELIN SIGNALING EXACERBATES ULCERATIVE COLITIS IN OLDER MICE
por: Wu, Chia-Shan, et al.
Publicado: (2019)

Identification of differentially expressed genes in ulcerative colitis and verification in a colitis mouse model by bioinformatics analyses
por: Shi, Lei, et al.
Publicado: (2020)

Animal Models and Pathogenesis of Ulcerative Colitis
por: Gao, Xin, et al.
Publicado: (2022)

Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis
por: Li, Heng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4vgv5vfg38psu33eudcdr3o72b