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Calcium-sensing receptor promotes high glucose-induced myocardial fibrosis via upregulation of the TGF-β(1)/Smads pathway in cardiac fibroblasts
Diabetic cardiomyopathy (DCM) is a major complication of diabetes and myocardial fibrosis is its major pathological feature. Calcium-sensing receptor (CaSR) is a G protein-coupled receptor and participates in the regulation of calcium homeostasis; it is implicated in a range of diseases, including m...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625450/ https://www.ncbi.nlm.nih.gov/pubmed/31173208 http://dx.doi.org/10.3892/mmr.2019.10330 |