CBP-1 Acts in GABAergic Neurons to Double Life Span in Axenically Cultured Caenorhabditis elegans

When cultured in axenic medium, Caenorhabditis elegans shows the largest life-span extension compared with other dietary restriction regimens. However, the underlying molecular mechanism still remains elusive. The gene cbp-1, encoding the worm ortholog of p300/CBP (CREB-binding protein), is one of t...

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Detalles Bibliográficos
Autores principales: Cai, Huaihan, Dhondt, Ineke, Vandemeulebroucke, Lieselot, Vlaeminck, Caroline, Rasulova, Madina, Braeckman, Bart P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
The Journal of Gerontology: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625597/
https://www.ncbi.nlm.nih.gov/pubmed/29099917
http://dx.doi.org/10.1093/gerona/glx206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625597/
https://www.ncbi.nlm.nih.gov/pubmed/29099917
http://dx.doi.org/10.1093/gerona/glx206

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