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CBP-1 Acts in GABAergic Neurons to Double Life Span in Axenically Cultured Caenorhabditis elegans

When cultured in axenic medium, Caenorhabditis elegans shows the largest life-span extension compared with other dietary restriction regimens. However, the underlying molecular mechanism still remains elusive. The gene cbp-1, encoding the worm ortholog of p300/CBP (CREB-binding protein), is one of t...

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Detalles Bibliográficos
Autores principales:	Cai, Huaihan, Dhondt, Ineke, Vandemeulebroucke, Lieselot, Vlaeminck, Caroline, Rasulova, Madina, Braeckman, Bart P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	The Journal of Gerontology: Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625597/ https://www.ncbi.nlm.nih.gov/pubmed/29099917 http://dx.doi.org/10.1093/gerona/glx206

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