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The nasal methylome as a biomarker of asthma and airway inflammation in children

The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age 12.9 y), and measure DNA methylation (DNAm) with the Infinium MethylationEPIC BeadChip. We perform nasal Epigenome-Wide Asso...

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Detalles Bibliográficos
Autores principales:	Cardenas, Andres, Sordillo, Joanne E., Rifas-Shiman, Sheryl L., Chung, Wonil, Liang, Liming, Coull, Brent A., Hivert, Marie-France, Lai, Peggy S., Forno, Erick, Celedón, Juan C., Litonjua, Augusto A., Brennan, Kasey J., DeMeo, Dawn L., Baccarelli, Andrea A., Oken, Emily, Gold, Diane R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625976/ https://www.ncbi.nlm.nih.gov/pubmed/31300640 http://dx.doi.org/10.1038/s41467-019-11058-3

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