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Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function
Intestinal organoids have emerged as a powerful in vitro tool for studying intestinal biology due to their resemblance to in vivo tissue at the structural and functional levels. However, their sphere-like geometry prevents access to the apical side of the epithelium, making them unsuitable for stand...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625996/ https://www.ncbi.nlm.nih.gov/pubmed/31300688 http://dx.doi.org/10.1038/s41598-019-46497-x |