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Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein

Radiotherapy is a cornerstone of cancer management. The improvement of spatial dose distribution in the tumor volume by minimizing the dose deposited in the healthy tissues have been a major concern during the last decades. Temporal aspects of dose deposition are yet to be investigated. Laser-plasma...

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Detalles Bibliográficos
Autores principales:	Bayart, E., Flacco, A., Delmas, O., Pommarel, L., Levy, D., Cavallone, M., Megnin-Chanet, F., Deutsch, E., Malka, V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626007/ https://www.ncbi.nlm.nih.gov/pubmed/31300704 http://dx.doi.org/10.1038/s41598-019-46512-1

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