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A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons, for which there is no effective treatment. Previously, we generated a Caenorhabditis elegans model of ALS, in which the expression of dnc-1, the homologous gene of human d...

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Detalles Bibliográficos
Autores principales:	Ikenaka, Kensuke, Tsukada, Yuki, Giles, Andrew C., Arai, Tadamasa, Nakadera, Yasuhito, Nakano, Shunji, Kawai, Kaori, Mochizuki, Hideki, Katsuno, Masahisa, Sobue, Gen, Mori, Ikue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626054/ https://www.ncbi.nlm.nih.gov/pubmed/31300701 http://dx.doi.org/10.1038/s41598-019-46642-6

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