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Intra-articularly injected mesenchymal stem cells promote cartilage regeneration, but do not permanently engraft in distant organs

Intra-articular (IA) injection of mesenchymal stem cells (MSCs) promotes articular cartilage repair. However, cell fate and action after transplantation remain unclear. This study aimed at evaluating the biodistribution and efficacy of MSCs after IA injection. We used an immunocompetent, dual transg...

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Detalles Bibliográficos
Autores principales: Satué, María, Schüler, Christiane, Ginner, Nikole, Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626061/
https://www.ncbi.nlm.nih.gov/pubmed/31300685
http://dx.doi.org/10.1038/s41598-019-46554-5