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Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment
BACKGROUND: In solid organ transplant (SOT) recipients, transplant rejection during immune checkpoint inhibitor (ICI) treatment for cancer is a clinical problem. Donor-derived cell-free DNA (dd-cfDNA) can be detected in blood and is a sensitive biomarker for diagnosis of acute rejection in SOT recip...
Autores principales: | Hurkmans, Daan P., Verhoeven, Jeroen G. H. P., de Leur, Kitty, Boer, Karin, Joosse, Arjen, Baan, Carla C., von der Thüsen, Jan H., van Schaik, Ron H. N., Mathijssen, Ron H. J., van der Veldt, Astrid A. M., Hesselink, Dennis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626432/ https://www.ncbi.nlm.nih.gov/pubmed/31300068 http://dx.doi.org/10.1186/s40425-019-0653-6 |
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